No, I've never looked into it. The only thing that's ever even crossed my mind to have some remote possibility of effectiveness into is astral travel through something like meditation.

There are so many people that recommend drugs like DMT or ayahuasca, but here's the giant hangup for me: I have yet to hear a single one of these people report back with something I would consider "insight" or "anomalous knowledge". That is, something unusual and important beyond the things I was able to find out by thinking about stuff and looking things up on the Internet. They also have an extremely hard time articulating what they claim to have learned and, trust me, I'm listening closely.

And you're ahead of me on the iodine. Oddly, I take it myself but only because I once read "everyone's deficient in iodine!" on the Internet, and then one day I had to pad an online order for free shipping. The strong effect it had is that I sleep like a baby. But hey, maybe my pineal is in good shape and my clarity of thought is great, but not yet enough to have noticed that clarity... lol.