Whose genetic program and for what purpose? That is the key question.
When it is completely up to you, say, you want to have a renewable teeth (just new one grow if something wrong with old) and you have exact map of what nucleotide sequence responsible for and change one that responsible for growing new tooth instead old one - what is the problem? It is your decision, you do it by yourself and no corporation could insert something unintended into your DNA. You just get always perfect teeth and will never have to pay dentist. Why could it be something wrong?
I'd rather care about teeth I have so I don't learn vanity in my life and just stop caring due disposable nature of my body.
I would not mind be able to repair shit I break due being idiot, which I admittedly am, but I'd rather not mess with my stock settings.
Of course there is speculative part of "what if accident", but then, I need material to learn on and from experience, making mistakes and dealing with consequences is path to improve.
Reasonable, me, probably, too. At least to the moment I will get a full and complete documentation on every possible setting. But why make a taboo from it? Bad guys (? transgender inhumans?) don't care about your taboos and will do that in any case.
I need material to learn on and from experience, making mistakes and dealing with consequences is path to improve.
This. Older civilisation - more consequences to deal with. You will have to deal with consequences of gene editing usage. For now, you already have to deal with consequences of mRNA gene editing. And how you will fix it if you deny gene editing technology as whole?
It is not taboo for me. Let me expand a bit on what I tried to express. If I can comprehend what given process does, I can estimate by myself consequences and risk to reward ratio (if any). For example they come up with some new whatever radio or any EM based tech , say some scanning techniques (like MRI) . I have provable skillset to asses what I'm dealing with before I go for this process, without need to trust 3rd party.
Also I have a problem with trusting things like that tech for a reason. I have to assume authority or so called expert in something that may be determinal for my well-being. By doing so I unintentionally turn off drive to know it, because "there is some one doing this 4433 years and knows better". As result I'm building my understanding of reality on somebody's else word (possibly agenda).
You don't need authority or expert to trust. Really, there are no things in the world that sane person could not comprehend.
As for the discussed CRISPR technology there is nothing complex at all. Special proteine split DNA and compare one strand with provided short RNA If RNA is complement to splitted part of DNA this proteine cuts/change nucleotide/whatever at that position. It is some kind of text search function in programming. You have a word, you have a text, you search a word in a text, if found, do something with text at that position - replace a word, letter or delete something. Simple, isn't it, if you get rid of all that biomedical slang?
The problem with that extremely simple thing is that to do something sensible you have to know exactly what you want to change and what will be the result. And that is the problem.
Really, things are not complex too. DNA is a program. 3 pairs of nucleotides (codons) progam an aminoacid. Some codons program stop or start condition for reader. Proteins built from aminoacids, so sequence of codons from start to stop encode a protein. And so on. The problem is that nearly nobody really try to reverse engineer that programming language and system. Most just do random changes in the hope to get the needed result.
It is like some webmonkey, trying to get modern fancy web2.0 site at the deadline insert random pieces of code into some big project using Ctrl+V Ctrl+C (CRISPR) without any understanding how all that things work and what he is doing in the hope to get something that will look like needed website and will be paid by emplyer. Obviously, the result is awful for end user, but profitable for webmonkey and employer.
Sane programmer will study how computer works, how it execute code and what that code do, and then will change exactly what he need. But nobody do that. Evetually, there are no books "gene editing for beginners" or "complete apple DNA documentation".
That is the problem with gene editing, not your inability to understand how things work.
Whose genetic program and for what purpose? That is the key question.
When it is completely up to you, say, you want to have a renewable teeth (just new one grow if something wrong with old) and you have exact map of what nucleotide sequence responsible for and change one that responsible for growing new tooth instead old one - what is the problem? It is your decision, you do it by yourself and no corporation could insert something unintended into your DNA. You just get always perfect teeth and will never have to pay dentist. Why could it be something wrong?
I'd rather care about teeth I have so I don't learn vanity in my life and just stop caring due disposable nature of my body.
I would not mind be able to repair shit I break due being idiot, which I admittedly am, but I'd rather not mess with my stock settings.
Of course there is speculative part of "what if accident", but then, I need material to learn on and from experience, making mistakes and dealing with consequences is path to improve.
Reasonable, me, probably, too. At least to the moment I will get a full and complete documentation on every possible setting. But why make a taboo from it? Bad guys (? transgender inhumans?) don't care about your taboos and will do that in any case.
This. Older civilisation - more consequences to deal with. You will have to deal with consequences of gene editing usage. For now, you already have to deal with consequences of mRNA gene editing. And how you will fix it if you deny gene editing technology as whole?
It is not taboo for me. Let me expand a bit on what I tried to express. If I can comprehend what given process does, I can estimate by myself consequences and risk to reward ratio (if any). For example they come up with some new whatever radio or any EM based tech , say some scanning techniques (like MRI) . I have provable skillset to asses what I'm dealing with before I go for this process, without need to trust 3rd party.
Also I have a problem with trusting things like that tech for a reason. I have to assume authority or so called expert in something that may be determinal for my well-being. By doing so I unintentionally turn off drive to know it, because "there is some one doing this 4433 years and knows better". As result I'm building my understanding of reality on somebody's else word (possibly agenda).
You don't need authority or expert to trust. Really, there are no things in the world that sane person could not comprehend.
As for the discussed CRISPR technology there is nothing complex at all. Special proteine split DNA and compare one strand with provided short RNA If RNA is complement to splitted part of DNA this proteine cuts/change nucleotide/whatever at that position. It is some kind of text search function in programming. You have a word, you have a text, you search a word in a text, if found, do something with text at that position - replace a word, letter or delete something. Simple, isn't it, if you get rid of all that biomedical slang?
The problem with that extremely simple thing is that to do something sensible you have to know exactly what you want to change and what will be the result. And that is the problem.
Really, things are not complex too. DNA is a program. 3 pairs of nucleotides (codons) progam an aminoacid. Some codons program stop or start condition for reader. Proteins built from aminoacids, so sequence of codons from start to stop encode a protein. And so on. The problem is that nearly nobody really try to reverse engineer that programming language and system. Most just do random changes in the hope to get the needed result.
It is like some webmonkey, trying to get modern fancy web2.0 site at the deadline insert random pieces of code into some big project using Ctrl+V Ctrl+C (CRISPR) without any understanding how all that things work and what he is doing in the hope to get something that will look like needed website and will be paid by emplyer. Obviously, the result is awful for end user, but profitable for webmonkey and employer.
Sane programmer will study how computer works, how it execute code and what that code do, and then will change exactly what he need. But nobody do that. Evetually, there are no books "gene editing for beginners" or "complete apple DNA documentation".
That is the problem with gene editing, not your inability to understand how things work.