"Working with longevity startup Retro Bio, researchers used GPT-4b micro, a model trained on biological data rather than text, to reengineer Yamanaka factors, proteins that reprogram adult cells into stem cells.
The original 2012 discovery converted less than 0.1% of cells over weeks, but the AI-designed versions achieved over 30% success rates and demonstrated superior DNA damage repair capabilities.
Multiple labs validated the results across different cell types and delivery methods, suggesting the approach could dramatically accelerate regenerative medicine and aging research from decades to weeks."
What are they going to do with this? Would they be able to keep seniors from dying?
Probably not the current crop, but perhaps those who will be seniors in forty to fifty years time.
Basically, as your cells senesce (get older), they lose functionality they had when they were younger. You get less robust error correction, slower healing, divison stoppage as telomeres run out, etc. This type of research is tackling one of those issues, the DNA degradation, that, if resolved, would allow older cells to function like younger cells.
Its not a potion of restore lost youth type thing, unfortunately. The field is too young for that yet.
"Working with longevity startup Retro Bio, researchers used GPT-4b micro, a model trained on biological data rather than text, to reengineer Yamanaka factors, proteins that reprogram adult cells into stem cells.
The original 2012 discovery converted less than 0.1% of cells over weeks, but the AI-designed versions achieved over 30% success rates and demonstrated superior DNA damage repair capabilities.
Multiple labs validated the results across different cell types and delivery methods, suggesting the approach could dramatically accelerate regenerative medicine and aging research from decades to weeks."
What are they going to do with this? Would they be able to keep seniors from dying?
Probably not the current crop, but perhaps those who will be seniors in forty to fifty years time.
Basically, as your cells senesce (get older), they lose functionality they had when they were younger. You get less robust error correction, slower healing, divison stoppage as telomeres run out, etc. This type of research is tackling one of those issues, the DNA degradation, that, if resolved, would allow older cells to function like younger cells.
Its not a potion of restore lost youth type thing, unfortunately. The field is too young for that yet.
You know such technology will never be accessible to the unwashed masses who will get poisoned and depoped instead.