But the Crigler-Najjar treatment has been indefinitely delayed, an Alexion spokeswoman told STAT. It never proved safe enough to test in humans, according to several former Moderna employees and collaborators who worked closely on the project. Unable to press forward with that technology, Moderna has had to focus instead on developing a handful of vaccines, turning to a less lucrative field that might not justify the company’s nearly $5 billion valuation.
“It’s all vaccines right now, and vaccines are a loss-leader,” said one former Moderna manager. “Moderna right now is a multibillion-dollar vaccines company, and I don’t see how that holds up.”
Bancel made no mention of the Crigler-Najjar drug when he spoke Monday before a similarly packed room at this year’s J.P. Morgan conference.
In need of a Hail Mary
Founded in 2012, Moderna reached unicorn status — a $1 billion valuation — in just two years, faster than Uber, Dropbox, and Lyft, according to CB Insights. The company’s premise: Using custom-built strands of messenger RNA, known as mRNA, it aims to turn the body’s cells into ad hoc drug factories, compelling them to produce the proteins needed to treat a wide variety of diseases.
But mRNA is a tricky technology. Several major pharmaceutical companies have tried and abandoned the idea, struggling to get mRNA into cells without triggering nasty side effects.
Maybe all the superclass are doing what the drug companies say because they were informed that those companies are within striking distance of real life-extension technology.
Maybe they were told that if they don't play along, "No life-extension for you!"
Yes, I agree, a longer time from infection to death is also a possibility - like HIV.
All a lucky coincidence for some people who had $billions invested
2017 - Lavishly funded Moderna hits safety problems in bold bid to revolutionize medicine
In need of a Hail Mary
Maybe all the superclass are doing what the drug companies say because they were informed that those companies are within striking distance of real life-extension technology.
Maybe they were told that if they don't play along, "No life-extension for you!"