An immune compromised loved one caught a bad version of whatever strain was going around last summer. Infection wasn’t clearing and fever getting too high. Prescribed five days of Paxlovid monoclonal antibody pills. Knocked the infection right out.

So as of at least last July this stuff was working.

Added: Loved one was not vaxxed and has not had Covid in any form or even as much as a cold before or since due to healthy lifestyle, avoiding crowds within reason but not being a hermit or wearing masks, lots of healthy foods and supplements and sunshine and exercise. These may also have been a factor in recovery.