The variants analyzed vary in frequency between different populations.
Our findings suggest a link between ACE2 variations and infection risk.
Our data suggest that ACE2 variants in different populations could cause significant variations in the binding affinity between SARS-CoV-2 and ACE2. Yet, experimental binding assays are still needed to confirm our claim.
Doesn't the Israeli day contradict this? Or did they totally fuck themselves with vaccines and remove their resistance?
ACE2 coding variants in different populations and their potential impact on SARS-CoV-2 binding affinity
https://www.sciencedirect.com/science/article/pii/S2405580820301072
Highlights
ACE2-K26R decreases SARS-CoV-2/ACE2 electrostatic attraction.
ACE2-I468V, R219C, K341R, D206G, G211R increase electrostatic attraction.
The variants analyzed vary in frequency between different populations.
Our findings suggest a link between ACE2 variations and infection risk.
Our data suggest that ACE2 variants in different populations could cause significant variations in the binding affinity between SARS-CoV-2 and ACE2. Yet, experimental binding assays are still needed to confirm our claim.