Spike protein can bind/interact with platelets. If you're churning out naked spike proteins, the platelets will appear dusted with the exogenous protein. The body may erroneously learn that platelets are the bad guys.
This is less likely with a full virus attached because the "training set" you're presenting has more details and parameters.
It's like trying to train an AI to recognize a dog by a picture of its foot vs the entire dog itself.
Hmm...autoimmune attack of his platelets?
Spike protein can bind/interact with platelets. If you're churning out naked spike proteins, the platelets will appear dusted with the exogenous protein. The body may erroneously learn that platelets are the bad guys.
This is less likely with a full virus attached because the "training set" you're presenting has more details and parameters.
It's like trying to train an AI to recognize a dog by a picture of its foot vs the entire dog itself.