Not at all a specialist in genetics or biology, but have had some schooling in those subjects. It’s true that there could be some defects from overly insular breeding (especially more directly incestuous relationships). This is because it enhances the probability of an offspring being homozygous dominant for a disease carrying allele (like hemophilia). Basically, insular breeding makes problematic traits in the gene pool more likely to be expressed. That being said, from what I’ve read, some now think the dangers of this might have been overstated a bit. Even though that kind of strict adherence to bloodlines opens up the risk for defects, it doesn’t inevitably lead to defects.

There’s definitely been some medical problems you can point to with royals and aristocrats, but overall most don’t have major health problems that I’m aware of. But they may have some other problems like the OP is pointing out.

I think it’s a really interesting theory. He might be on to something.

Not at all a specialist in genetics or biology, but have had some schooling in those subjects. It’s true that there could be some defects from overly insular breeding (especially more directly incestuous relationships). This is because it enhances the probability of an offspring being homozygous dominant for a disease carrying allele (like hemophilia). Basically, insular breeding makes problematic traits in the gene pool more likely to be expressed. That being said, from what I’ve read, we now think the dangers of this might have been slightly overstated. Even though that kind of strict adherence to bloodlines opens up the risk for defects, There’s definitely been some medical problems you can point to with royals and aristocrats, but overall most don’t have major health problems that I’m aware of. But they may have some other problems like the OP is pointing out.

I think it’s a really interesting theory. He might be on to something.

Not at all a specialist in genetics or biology, but have had some schooling in those subjects. It’s true that there could be some defects from overly insular breeding (especially more directly incestuous relationships). This is because it enhances the probability of an offspring being homozygous dominant for a disease carrying allele (like hemophilia). Basically, makes potentially problematic traits in the gene pool from being expressed. That being said, from what I’ve read, we now think the dangers of this might have been slightly overstated. There’s been some medical problems you can point to with royals and aristocrats, but overall most don’t have major health problems that I’m aware of. But they may have some other problems like the OP is pointing out.

I think it’s a really sound theory