one should be able prove or disprove the THEORY of evolution in a lifetime by performing the right experiment. Start off experimenting on something with a short life span and choose the right stimulus to expose it to. We are talking about things like bacteria here and the obvious choice would be to expose the bacteria to an increasing amount of something that kills bacteria such as titrating up a concentration of bleach. the same could be done with brewers yeast and alcohol if it was desired to have an end result that was functional and profitable. "non-GMO" yeast used in brewing in high-test beer.