Men is a reference to Christ. Two men would be a reference to Christ and Antichrist.

If it was a man and a woman, it would be a reference to Christ and the Church. If one of them was taken, and the other not, spiritually that would not make sense.

In the KJV, even if something does not make sense in a natural way, there is a spiritual lesson there, that will confound the natural mind. Pray and ask for guidance, and God will show those with faith what is right, and what is not, when it comes to the word.