AZ, J&J and Sputnik are all viral vector vaccines, which work through a DNA payload. I.e. nothing new.
BS.
Viral vector in the sense of J&J is completely new, and it's just mRNA with extra steps. They get a virus, in this case a chimp adenovirus, and put DNA into it yes. But what happens to it? Once the trojan horse adenovirus gets it into your cells it unpacks and is converted into mRNA, which then tells your cells to make the protein.
The ONLY viral vector rollout in humans before this was ebola, a few thousand in the democratic republic of congo, and like the covid jabs, it was only given emergency authorization in the US and EU in 2019 or so. 2 years old, with very limited rollout in a place you can't really track long term results well.
'Live attenuated' and 'live inactivated' is the old method you might be thinking of, it's where they take the whole virus they mean to immunise you against, like polio. They weaken and kill the thing so that it won't (usually) do any harm as your body learns to fight the whole thing. (the 2 other old methods are subunit, like NOVAVAX, and toxoid, like the tenanus shots)
Viral vector is NOT this old method, it is a means to get DNA into your cells, in order to make them do something. In this case, it is converted into mRNA.
I don't care if the mRNA is directly injected or it has extra steps, these new methods are new and untested. Please stop spreading the misinformation that J&J is in anyway based on old tech. Viral vector just SOUNDS like it is using that old method. It is very new.
If you want to discuss polio, well then, that's a whole other can of worms. Useless stuff, those vaccines. Polio was DDT/heavy metal poisoning, and a range of other neurological diseases they split that polio up into. It disappeared almost by better differential diagnosis alone. Getting children of the land, away from child labor, picking pesticized fruits, and stopping spraying DDT, on the land, in the house, "cured" it.
The miracle story of vaccines. What a joke. No vax = healthy kids.
Sorry, I know my stuff. I analyzed convid from day 1. And you misinterpret my words. I never said it's old, I say it's not new, as the title of this post seems to intend to convey. "2.0" Viral vector, adenovirus or AAV based, are used in gene therapy products already on the market, as well as in the J&J, AZ, and Sputnik tech, which were already put in millions of arms.
Here the information on AZ and J&J, showing you they contain DNA. Viral vector delivers this DNA to the cell nucleus, where most of our genome is located.
AZ:
"Adenoviruses such as AZD1222 are non-encapsulated, icosahedral particles (virions) between 80 and 100 nm in diameter. The particles contain a single copy of the double-stranded DNA genome."
COVID-19 Vaccine Janssen (also referred to as Ad26.COV2.S) is a monovalent, recombinant, replication-incompetent adenovirus type 26 (Ad26) vectored vaccine encoding a severe acute respiratory syndrome coronavirus 2 (SARS CoV 2) spike (S) protein. Wild-type adenovirus serotype 26 (Ad26) consists of non-enveloped virions, which encode the adenoviral proteins. The dsDNA molecule is encapsulated by an icosahedral protein structure.
It's just one of the biggest lies I see floating round, that J&J is old tech, they're trying to trick people wary of the mRNA into taking viral vector, cause it sounds like the live attentuated/inactivation vaccines we've all already had a few of.
Yes, i fully agree. I've seen this as well, many people thought AZ was a "classical" vaccine, and still do. I got downvoted and banned for saying it wasn't. Not that classical vaccines are any good, they're all poison, but that's another matter.
AZ, J&J and Sputnik are all viral vector vaccines, which work through a DNA payload. I.e. nothing new. Freedom of choice: pick your genetic poison.
BS.
Viral vector in the sense of J&J is completely new, and it's just mRNA with extra steps. They get a virus, in this case a chimp adenovirus, and put DNA into it yes. But what happens to it? Once the trojan horse adenovirus gets it into your cells it unpacks and is converted into mRNA, which then tells your cells to make the protein.
The ONLY viral vector rollout in humans before this was ebola, a few thousand in the democratic republic of congo, and like the covid jabs, it was only given emergency authorization in the US and EU in 2019 or so. 2 years old, with very limited rollout in a place you can't really track long term results well.
'Live attenuated' and 'live inactivated' is the old method you might be thinking of, it's where they take the whole virus they mean to immunise you against, like polio. They weaken and kill the thing so that it won't (usually) do any harm as your body learns to fight the whole thing. (the 2 other old methods are subunit, like NOVAVAX, and toxoid, like the tenanus shots)
Viral vector is NOT this old method, it is a means to get DNA into your cells, in order to make them do something. In this case, it is converted into mRNA.
I don't care if the mRNA is directly injected or it has extra steps, these new methods are new and untested. Please stop spreading the misinformation that J&J is in anyway based on old tech. Viral vector just SOUNDS like it is using that old method. It is very new.
If you want to discuss polio, well then, that's a whole other can of worms. Useless stuff, those vaccines. Polio was DDT/heavy metal poisoning, and a range of other neurological diseases they split that polio up into. It disappeared almost by better differential diagnosis alone. Getting children of the land, away from child labor, picking pesticized fruits, and stopping spraying DDT, on the land, in the house, "cured" it.
The miracle story of vaccines. What a joke. No vax = healthy kids.
Sorry, I know my stuff. I analyzed convid from day 1. And you misinterpret my words. I never said it's old, I say it's not new, as the title of this post seems to intend to convey. "2.0" Viral vector, adenovirus or AAV based, are used in gene therapy products already on the market, as well as in the J&J, AZ, and Sputnik tech, which were already put in millions of arms.
Here the information on AZ and J&J, showing you they contain DNA. Viral vector delivers this DNA to the cell nucleus, where most of our genome is located.
AZ:
"Adenoviruses such as AZD1222 are non-encapsulated, icosahedral particles (virions) between 80 and 100 nm in diameter. The particles contain a single copy of the double-stranded DNA genome."
Page 15 of the EPAR: https://www.ema.europa.eu/en/documents/assessment-report/vaxzevria-previously-covid-19-vaccine-astrazeneca-epar-public-assessment-report_en.pdf
J&J:
COVID-19 Vaccine Janssen (also referred to as Ad26.COV2.S) is a monovalent, recombinant, replication-incompetent adenovirus type 26 (Ad26) vectored vaccine encoding a severe acute respiratory syndrome coronavirus 2 (SARS CoV 2) spike (S) protein. Wild-type adenovirus serotype 26 (Ad26) consists of non-enveloped virions, which encode the adenoviral proteins. The dsDNA molecule is encapsulated by an icosahedral protein structure.
Page 17: https://www.ema.europa.eu/en/documents/assessment-report/covid-19-vaccine-janssen-epar-public-assessment-report_en.pdf
Ok fair enough
It's just one of the biggest lies I see floating round, that J&J is old tech, they're trying to trick people wary of the mRNA into taking viral vector, cause it sounds like the live attentuated/inactivation vaccines we've all already had a few of.
Yes, i fully agree. I've seen this as well, many people thought AZ was a "classical" vaccine, and still do. I got downvoted and banned for saying it wasn't. Not that classical vaccines are any good, they're all poison, but that's another matter.