Dot connector post...
The company uniQure has concluded that a virus used widely in gene therapy was very unlikely to have caused liver cancer in a hemophilia patient in a clinical trial.
The tumor, detected in December 2020, raised concerns that the adeno-associated virus (AAV) used to carry a loop of DNA into the patient’s liver cells had inadvertently switched on a cancer gene. But uniQure’s tests of the patient’s tumor cells showed the AAV inserted into the genome in only a tiny fraction (0.027%) of the cells, and when it did, it landed in randomly scattered spots. If the AAV had triggered a single cell to grow out of control, the viral DNA would have shown up in the same spots in lots of the tumor cells.
Let's play God shall we?