13 That explains a lot... (media.conspiracies.win) posted 143 days ago by SmithW1984 143 days ago by SmithW1984 +14 / -1 9 comments download share 9 comments share download save hide report block hide replies
How is low testosterone diagnosed? has anything changed to the tests since 1960s?
Yes, it has. This may have inflated measured T levels in the past. Still the decline trend of 1% per year can be established even if looking at the past decade or so.
1960s–80s Radioimmunoassay (RIA) Lower specificity, cross-reactivity issues
1990s–2000s Improved RIA and early mass spectrometry (MS) Moderate accuracy
2010s–Present Liquid chromatography–mass spectrometry (LC-MS/MS) Gold standard: high precision & specificity