Boy, your all over the place. And even your end result that your trying to get to is iffy at best.

https://pro.endocrineweb.com/endocrinology/does-marijuana-adversely-impact-endocrine-system

"However, several other studies have had results that contradict the CARDIA study findings. A Harvard Medical School study found lower fasting insulin levels and less insulin resistance among marijuana users⁴ and Michigan State University researchers analyzed eight different studies with findings that indicated a 30% reduction in diabetes risk among marijuana users.⁵"

You know what came up when looking into this subject?

https://www.sciencedirect.com/science/article/pii/S2468227619306969 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071457/

Its got to be the plant thats been smoked for thousands of years, not the plastics or other pollutants, right, right?

Anyway, the main irk I have is you are assuming they bind to the same receptors. They dont.

THC and CBD bind with cannabinoid receptors (CB1 and CB2)

Classically, the biological effects of estrogens are mediated through their interaction with estrogen receptor alpha (ERα) and beta (ERβ).

https://academic.oup.com/endo/article/153/3/1016/2423624

Initial cannabinoid research suggested that THC may exert some of its effects by interacting directly with estradiol receptors. Some studies have suggested that both crude cannabis extract and THC inhibit the binding of estradiol to estradiol receptors in vivo (60–62). However, more recent studies have not been able to replicate these estradiol binding effects using either THC, other cannabinoids such as cannabinol, or THC metabolites (63, 64).

There is some evidence to suggest it can block testosterone though. Not much, Iffy.

The endocannabinoid system appears to regulate serum levels of gonadal hormones and gonadotrophins. Several earlier studies investigated whether use of marijuana in human males is associated with changes in levels of gonadal hormones or gonadotropins. Chronic marijuana use reduces levels of circulating testosterone, FSH, and LH levels (15, 16). Acute administration of marijuana also can reduce testosterone and LH levels (15, 17). However, others have reported no effects on circulating testosterone, LH, or FSH levels in response to either chronic marijuana or chronic THC hormones (18–22). The discrepancies among studies using human participants may be due to individual differences among the participants in the amounts consumed, and methodological differences between studies. The influence of cannabinoids on androgens appears to be more consistent in animal models.

Its got to be the plant though right, not the people raping the planet and its people for profit. Yeah, must be.

Here's a quick link I found for you.

https://www.sciencedirect.com/topics/medicine-and-dentistry/cannabinoid-receptor#:~:text=Cannabinoid%20receptors%20are%207%2Dtransmembrane,marijuana%20to%20ganja%20and%20bhang.