Prof. Dr Dolores Cahill is a world-wide renowned expert in high-throughput proteomics technology development and automation, high content protein arrays and their biomedical applications, including in biomarker discovery and diagnostics.
Prof. Cahill pioneered this research area at the Max-Planck-Institute of Molecular Genetics in Berlin, Germany, and holds several international patents in this field with research, biomedicine and diagnostic applications.
oOver 20 years expertise in high-throughput protein & antibody array, automation, proteomics technology development & biomedical applications in biomarker discovery, diagnostics & personalised medicine.
oSince 2005 to present, Full Professor of Translational Science, School of Medicine, University College Dublin, Academic, Researcher, Lecturer, Module Coordinator in Pathology Teaching, School of Medicine & Conway Institute
-15 years as Irish, EU & international expert & advisor including Seconded National Expert to European Commission
-Company Co-founder & Shareholder (1997-2019) of Protagen AG in Germany (https://protagen.com/). Protagen Protein Services (2012-2019) contract services to healthcare sector & pharmaceutical industry (https://protagenproteinservices.com/).
-Since 2016, co-founding shareholder and Advisory Board member of Prof. Stephen Pennington’s UCD School of Medicine/Conway Institute spin-out company, Atturos Ltd. working to improve Prostate Cancer diagnosis (http://atturos.com/ and http://atturos.com/company/advisors/).
-Prof. Cahill has a total of over 5940 Citations, H (Hirsh)-index of 35, i10-index of 48.
-Project management: Has successfully obtained and project managed as Principal Investigator eight EU Programme funding grants from FP4, FP5, FP6, FP7 and Horizon 2020, Science Foundation Ireland, Enterprise Ireland, Health Research Board funding in companies and universities.
Selected Academic Leadership and Contributions: Member of Committees and Awards:
In 2013-2014, worked in European Commission, Brussels seconded full-time, as a Seconded National Expert (SNE) to the European Commission Research & Innovation (HORIZON2020) (DG RTD) Directorate, in a Strategy and Policy Development role for International R&D&I Cooperation between the EU & Asia (S. Korea, China, ASEAN) & for the Coordination of Health Research, Development and Innovation globally.
In 2005, appointed by the Irish Prime Minister (Taoiseach) & Minister for Health as an Irish Government’s Advisory Science Council (ASC) Member (www.sciencecouncil.ie) (2005-2013) & to develop Irish Strategy for Science, Technology & Innovation (2006-2013) with Universities, Industry & Health, Education, Enterprise & Finance Depts.
Chaired the ASC Task Force ‘Towards a Framework for Researcher Careers’ & ASC Task Force member Report on ‘Promoting Enterprise-Higher Education Relationships’ (2009) and ‘Sustainability of Research Centres’ (2012)
Honoured with a lifetime award from the Federation of European Biochemical Societies Award in Norway (2009) for her research & its significance. Other awardees: Prof. J. Craig Venter & Nobel Prize winner, Prof. Robert Huber.
Awarded the prestigious BMBF BioFuture Prize by German Minister of Science (€1.5million) (2000).
Supervisor of over 20 completed PhD & Masters’ degrees in total. Chair of ten UCD PhD committees.
Project management, Research and Peer-Reviewed Publications:
Prof. Cahill has a Hirsch h-index 35: i10-index 48.
13th-14th September 2018: Speaker, 5th Precision Medicine & Biomarkers Leaders’ Summit, Munich & Chair of Roundtable on Personalised Medicine & Adverse Events (http://www.giiconference.com/gel560004/catalog.pdf?1528437050).
-9th March 2020: Prof. Cahill invited to speak on the panel ‘A View from the Top: UCD Medicine Female Professors in Conversation’ to mark International Women's Day 2020 (https://www.ucd.ie/medicine/whatson/title,485524,en.html)
-17th-21st September 2017: HUPO2017: Human Proteome Organising (HUPO) Committee Member. The Annual HUPO World meeting was held in Dublin. UCD Prof. Stephen Pennington was Conference Chair. Prof. Cahill was HUPO 2017 Chief Financial Officer (http://hupo2017.ie/?team=prof-dr-dolores-cahill) & had over 1300 attendees with 90% from outside Ireland. Total budget € 1,300,000 & small profit made was returned to the sponsor, British Proteome Society. USA Vice-President (http://hupo2017.ie/news-2/) launched Global Cancer Moonshot at Conference Gala dinner.
·Anti-ribosomal-phosphoprotein autoantibodies penetrate to neuronal cells via neuronal growth associated protein (GAP43), affecting neuronal cells in-vitro. Kivity, Shaye; Shoenfeld, Yehuda; Arango, Maria Terresa; Cahill, Dolores J; O'Kane, Sara Louise; Zusev, Margalit; Slutsky, Inna; Harel-Meir, Michal; Chapman, Joab; Mathias, Torsten; Blank, Miri. (2017) Rheumatology RHE-15-1025.
·Ligand-directed targeting of lymphatic vessels uncovers mechanistic insights in melanoma metastasis D. R. Christiansona, A. S. Dobroffb, B. Pronetha,A. J. Zuritad, A. Salameha, et al., D. J. Cahill, J. E. Gershenwaldg, R. L. Sidmanj, Wadih Arap, R. Pasqualini (2015) Proceedings of the National Academy of Sciences PNAS USA 2015 Feb 6. pii: 201424994. PMID: 25659743 www.pnas.org/cgi/doi/10.1073/pnas.1424994112.
·Highly sensitive toxin microarray assay to improve Aflatoxin B1 detection in food. Beizaei A, O’ Kane SL, Kamkar A, Misaghi A, Henehan G, Cahill DJ. (2015) Food Chemistry Vol 57: 210–215 DOI:10.1016/j.foodcont.2015.03.039.
[.../...]
UNIVERSITY COLLEGE DUBLIN APPOINTMENTS
Full Professor
University College Dublin, School of Medicine, Dublin 4, Ireland1 Oct 2010
DEGREES
BA
Trinity College Dublin
PhD
Dublin City University (DCU) IRL
Dolores is an Inventor, Founder and Shareholder of Companies, has been Granted & licensed Patents in Europe, USA & worldwide with applications in improving the early accurate diagnosis of disease (auto immune diseases & cancer). Click here to visit her University College Dublin School of Medicine public profile.
Her latest business ventures include the World Freedom Alliance, FreedomAirway and Custodean.
With more than 20 years expertise in high-throughput protein & antibody array, proteomics technology development, automation & biomedical applications in biomarker discovery, diagnostics & personalised medicine
Selected experience as Expert in EU over past 15 years: EU Future & Emerging technologies (FETOPEN) Innovation Launchpad; EU Innovation Radar Expert, EU Horizon 2020 Societal Challenges 1 (Health).
Holds several granted and licensed international patents (EU, USA, Japan, Australia) (1995-present) and peer reviewed publications, and reports,
Professor, University College Dublin (2005-present)
Group Leader, Max-Planck-Institute, Berlin, Germany (1995-2003)
Supervisor of completed PhD & Masters’ degree students in Germany and Ireland.
Co-founded Protagen AG in Dortmund (https://protagen.com/) (1996-2019) as a spin-out of the Max-Planck-Institute, Berlin to commercialise her diagnostic, companion diagnostic and personalised medicine applications of her discoveries. Protagen has screened and profiled the autoantibody repertoire of over 20,000 patients (https://protagen.com/data-and-insight/scientific-publications/)
Protagen Protein Services (https://protagenproteinservices.com/) a spin-off company of Protagen since 2013 - expertise in protein, antibody, proteomics and peptide contract services to the pharmaceutical industry and health care sectors.
Policy and Strategy: Developing Research Infrastructure Sustainability & Integrated Healthcare Systems:
Member, Irish Government’s Advisory Science Council (ASC) Member (sciencecouncil.ie) (2005-2013) for Science, Technology & Innovation.
Dolores was an ASC Task Force member on ASC Policy Reports on ‘Promoting Enterprise-Higher Education Relationships’ (2009) & ‘Sustainability of Research Centres’ (2012).
Dolores chaired the ASC Task Force for Government Policy ‘Towards a Framework for Researcher Careers’ (2008).
Seconded National Expert (SNE) (2013-2014) to the European Commission Research and Innovation Directorate, in a Strategy and Policy Development role for International R&D&I Cooperation.
Award from the Federation of European Biochemical Societies Award in Norway Research and its significance.
Awarded BMBF BioFuture Prize by German Minister of Science.
Research, Scholarship and Innovation: Recent Keynotes and Conferences organised:
Member of the Organizing Committee of the Annual World Proteome HUPO Organisation 2017 meeting held in Dublin in September 2017, chaired by UCD Prof. Stephen Pennington. Conference Gala dinner was opened by USA Vice-President Joseph R. Biden (http://hupo2017.ie/news-2/).
Invited to give Lectures and Keynotes at conferences including in USA, Europe, China, Japan, South Korea, Australia, South America. Recent lectures include at Companion Diagnostics & Biomarkers Conference 2019 in Porto, 13th and 14th February 2019; 5th Precision Medicine & Biomarkers Leaders’ Summit, Munich, Sept 2018 & Chair Roundtable on Personalised Medicine & Adverse Events: (http://www.giiconference.com/gel560004/catalog.pdf?1528437050).
Research, Scholarship and Innovation including Policy and Strategy:
Expert in EU European Commission for 15 years, including Future & Emerging technologies (FETOPEN); Innovation Radar Expert; H2020 Societal Challenges 1 (Health); European Research Council.
Previously participated in evaluations for BMBF/DLR in Germany; UK BBSRC; Vinnova in Sweden; IWT in Belgium.
Examples of Science Advisory Boards Membership over past 15 years: Human Protein Atlas, Sweden; ProNova Research Institute Sweden; Complexinc, Switzerland; Atturos Ltd, Dublin.
Policy and Strategy - Seconded National Expert to the European Commission, Brussels:
Seconded as a National Expert in Policy to Brussels to European Commission Research & Innovation (1.10.2013- 30.9.2014) - International Cooperation for Strategy and Policy coordination.
Prof. Dr Dolores Cahill is a world-wide renowned expert in high-throughput proteomics technology development and automation, high content protein arrays and their biomedical applications, including in biomarker discovery and diagnostics.
Prof. Cahill pioneered this research area at the Max-Planck-Institute of Molecular Genetics in Berlin, Germany, and holds several international patents in this field with research, biomedicine and diagnostic applications. oOver 20 years expertise in high-throughput protein & antibody array, automation, proteomics technology development & biomedical applications in biomarker discovery, diagnostics & personalised medicine. oSince 2005 to present, Full Professor of Translational Science, School of Medicine, University College Dublin, Academic, Researcher, Lecturer, Module Coordinator in Pathology Teaching, School of Medicine & Conway Institute
-15 years as Irish, EU & international expert & advisor including Seconded National Expert to European Commission
-Company Co-founder & Shareholder (1997-2019) of Protagen AG in Germany (https://protagen.com/). Protagen Protein Services (2012-2019) contract services to healthcare sector & pharmaceutical industry (https://protagenproteinservices.com/). -Since 2016, co-founding shareholder and Advisory Board member of Prof. Stephen Pennington’s UCD School of Medicine/Conway Institute spin-out company, Atturos Ltd. working to improve Prostate Cancer diagnosis (http://atturos.com/ and http://atturos.com/company/advisors/). -Prof. Cahill has a total of over 5940 Citations, H (Hirsh)-index of 35, i10-index of 48.
-Project management: Has successfully obtained and project managed as Principal Investigator eight EU Programme funding grants from FP4, FP5, FP6, FP7 and Horizon 2020, Science Foundation Ireland, Enterprise Ireland, Health Research Board funding in companies and universities.
Selected Academic Leadership and Contributions: Member of Committees and Awards:
-Vice Chair, European Union Innovative Medicines Initiative Scientific Committee (2018-2021) and Member, European Union Innovative Medicines Initiative Scientific Committee (2016-2021) and Vice-Chair (2018-2021) (https://www.imi.europa.eu/sites/default/files/uploads/documents/About-IMI/Governance/sc/IMI_SC_Bio_Dolores_Cahill.pdf).
Project management, Research and Peer-Reviewed Publications:
Selected Academic Leadership and Contributions: Invited Speaker, Keynotes, Conferences organised:
Selected Peer Reviewed Publications:
· Medical Errors & Adverse Events: leading cause of death and disease burden. Cahill, Dolores (2018) Health Europa: 7:42-43. (http://edition.pagesuite-professional.co.uk/html5/reader/production/default.aspx?pubname=&edid=73e202a8-1e25-4d2e-afc3-1cd95c26e5ae)
·Anti-ribosomal-phosphoprotein autoantibodies penetrate to neuronal cells via neuronal growth associated protein (GAP43), affecting neuronal cells in-vitro. Kivity, Shaye; Shoenfeld, Yehuda; Arango, Maria Terresa; Cahill, Dolores J; O'Kane, Sara Louise; Zusev, Margalit; Slutsky, Inna; Harel-Meir, Michal; Chapman, Joab; Mathias, Torsten; Blank, Miri. (2017) Rheumatology RHE-15-1025.
·Ligand-directed targeting of lymphatic vessels uncovers mechanistic insights in melanoma metastasis D. R. Christiansona, A. S. Dobroffb, B. Pronetha,A. J. Zuritad, A. Salameha, et al., D. J. Cahill, J. E. Gershenwaldg, R. L. Sidmanj, Wadih Arap, R. Pasqualini (2015) Proceedings of the National Academy of Sciences PNAS USA 2015 Feb 6. pii: 201424994. PMID: 25659743 www.pnas.org/cgi/doi/10.1073/pnas.1424994112.
·Highly sensitive toxin microarray assay to improve Aflatoxin B1 detection in food. Beizaei A, O’ Kane SL, Kamkar A, Misaghi A, Henehan G, Cahill DJ. (2015) Food Chemistry Vol 57: 210–215 DOI:10.1016/j.foodcont.2015.03.039.
[.../...]
UNIVERSITY COLLEGE DUBLIN APPOINTMENTS
DEGREES
BA Trinity College Dublin PhD Dublin City University (DCU) IRL
https://people.ucd.ie/dolores.cahill
Dolores is an Inventor, Founder and Shareholder of Companies, has been Granted & licensed Patents in Europe, USA & worldwide with applications in improving the early accurate diagnosis of disease (auto immune diseases & cancer). Click here to visit her University College Dublin School of Medicine public profile.
Her latest business ventures include the World Freedom Alliance, FreedomAirway and Custodean.
With more than 20 years expertise in high-throughput protein & antibody array, proteomics technology development, automation & biomedical applications in biomarker discovery, diagnostics & personalised medicine
Selected experience as Expert in EU over past 15 years: EU Future & Emerging technologies (FETOPEN) Innovation Launchpad; EU Innovation Radar Expert, EU Horizon 2020 Societal Challenges 1 (Health).
Holds several granted and licensed international patents (EU, USA, Japan, Australia) (1995-present) and peer reviewed publications, and reports,
Professor, University College Dublin (2005-present)
Group Leader, Max-Planck-Institute, Berlin, Germany (1995-2003)
Supervisor of completed PhD & Masters’ degree students in Germany and Ireland.
Co-founded Protagen AG in Dortmund (https://protagen.com/) (1996-2019) as a spin-out of the Max-Planck-Institute, Berlin to commercialise her diagnostic, companion diagnostic and personalised medicine applications of her discoveries. Protagen has screened and profiled the autoantibody repertoire of over 20,000 patients (https://protagen.com/data-and-insight/scientific-publications/)
Protagen Protein Services (https://protagenproteinservices.com/) a spin-off company of Protagen since 2013 - expertise in protein, antibody, proteomics and peptide contract services to the pharmaceutical industry and health care sectors.
Policy and Strategy: Developing Research Infrastructure Sustainability & Integrated Healthcare Systems:
Over 15 years supporting initiatives to integrate research, biobanking, electronic health records in the health care sector, including integration of Biobanking & Biomarker Network (http://education.crdi.ie/page/g/s/91) and a long-term supporter of Biobanking Ireland, led by Prof. Eoin Gaffney (http://www.biobankireland.com/) and Clinical Research Development Ireland (https://www.crdi.ie/research/innovation/innovation-biographies/).
Scientific Review Board Member of the German Cancer Aid (Deutsche Krebshilfe) (2016-2020) evaluating research funding grant applications for Cancer research, including Clinical Trials in Germany. (https://www.krebshilfe.de/informieren/ueber-uns/deutsche-krebshilfe/about-us-deutsche-krebshilfegerman-cancer-aid/)
Member of the German International Science Advisory Review Board of the German Translational Medicine in Cancer (2010 – 2017) Strategic Programme funded by the German Department Health and the BMBF/DLF in Germany (http://www.dkfz.de/en/presse/pressemitteilungen/2011/dkfz-pm-11-24-German-Consortium-for-Translational-Cancer-Research-Gets-Started.php).
Member, Irish Government’s Advisory Science Council (ASC) Member (sciencecouncil.ie) (2005-2013) for Science, Technology & Innovation.
Dolores was an ASC Task Force member on ASC Policy Reports on ‘Promoting Enterprise-Higher Education Relationships’ (2009) & ‘Sustainability of Research Centres’ (2012).
Dolores chaired the ASC Task Force for Government Policy ‘Towards a Framework for Researcher Careers’ (2008).
Seconded National Expert (SNE) (2013-2014) to the European Commission Research and Innovation Directorate, in a Strategy and Policy Development role for International R&D&I Cooperation.
Award from the Federation of European Biochemical Societies Award in Norway Research and its significance.
Awarded BMBF BioFuture Prize by German Minister of Science.
Recent Article on the recognition and prevention of medical errors and adverse events: Medical Errors & Adverse Events: leading cause of death and disease burden. Dolores J. Cahill. (Health Europa Nov 2018: 7:42-43) (http://edition.pagesuite-professional.co.uk/html5/reader/production/default.aspx?pubname=&edid=73e202a8-1e25-4d2e-afc3-1cd95c26e5ae)
Research, Scholarship and Innovation: Recent Keynotes and Conferences organised:
Member of the Organizing Committee of the Annual World Proteome HUPO Organisation 2017 meeting held in Dublin in September 2017, chaired by UCD Prof. Stephen Pennington. Conference Gala dinner was opened by USA Vice-President Joseph R. Biden (http://hupo2017.ie/news-2/).
Invited to give Lectures and Keynotes at conferences including in USA, Europe, China, Japan, South Korea, Australia, South America. Recent lectures include at Companion Diagnostics & Biomarkers Conference 2019 in Porto, 13th and 14th February 2019; 5th Precision Medicine & Biomarkers Leaders’ Summit, Munich, Sept 2018 & Chair Roundtable on Personalised Medicine & Adverse Events: (http://www.giiconference.com/gel560004/catalog.pdf?1528437050).
Research, Scholarship and Innovation including Policy and Strategy:
Expert in EU European Commission for 15 years, including Future & Emerging technologies (FETOPEN); Innovation Radar Expert; H2020 Societal Challenges 1 (Health); European Research Council.
Previously participated in evaluations for BMBF/DLR in Germany; UK BBSRC; Vinnova in Sweden; IWT in Belgium.
Examples of Science Advisory Boards Membership over past 15 years: Human Protein Atlas, Sweden; ProNova Research Institute Sweden; Complexinc, Switzerland; Atturos Ltd, Dublin.
Policy and Strategy - Seconded National Expert to the European Commission, Brussels:
Seconded as a National Expert in Policy to Brussels to European Commission Research & Innovation (1.10.2013- 30.9.2014) - International Cooperation for Strategy and Policy coordination.
https://dolorescahill.com/pages/about