The gist of the idea is based on the thought of CDC being the same as 343, if you use a simple alphabet letter-to-number substitution cipher.

343 Industries is the company that makes Halo. They are based in Redmond, Washington, and got the Halo franchise from Bungie. Of course, Halo is the hallmark franchise for the Xbox, which is made by Microsoft. Bill Gates co-founded Microsoft, and greatly to contributes to the WHO and has raised money for the CDC as well.

But I think it's a bit deeper than that. 343 Industries got its name from 343 Guilty Spark, and from that page...

"Guilty Spark is an artificial intelligence whose primary role, as designated by his Forerunner makers, is to maintain his ringworld Installation 04, also known as 'Halo' as its caretaker, and to contain any infestation of the parasitic Flood species via the activation of the Halo arrays, which destroys all life in the galaxy in the process."

The Guilty Spark is rather similar to an all-seeing eye, and is rather indifferent to destruction of life. Though it helps Master Chief at times, it doesn't hesitate in trying to kill him if their objectives don't match.

The Halo arrays themselves weren't made to destroy the Flood, but to destroy the biomass that they thrive on. So while a galaxy may be destroyed, it could still be later repopulated. Now, the Flood themselves are interesting. They are a parasitic species, and infect the host, living or dead, by driving spines into the them to access their nervous system. Life forms that are changed into Flood can also similarly infect others. In the Wikipedia article, it describes the Flood as being portrayed as a "fungal zombie", but they were "based on the behavior of viruses and some bacteria".

There's oodles more to this I'm sure, like I'm leaving out the aliens (Covenant), but I just wanted to leave with a final thought. The guy who voiced Guilty Spark called him a "bastard", and think about his role as described via the Wikipedia article...

"Guilty Spark's role in the Halo series is cited as an example of a trend in video games where technology, not angels, is cast as an agent of revelation. In his book Halo and Philosophy: Intellect Evolved, Luke Cuddy suggested that Halo's handling of artificial intelligence shows that modern society more commonly associates the idea of revelation with technology then with divine forces, and that belief in God is unnecessary in order to long for understanding of the human situation since humanity's belief in the divine is in some ways being implanted by "faith" in technology. He compared Spark's role in disclosing the truth of the Halo installations to several major characters to that an angel: an otherworldly guide and mediator who escorts visionaries through potentially treacherous otherworldly terrain, interprets what they see so that it could be passed down as privileged information, and provides reassurance of a higher purpose on the face of the apocalypse. Spark's dialogue represents the "demythifying" power of naturalistic explanation, because he debunks the religious beliefs and superstitions of the Covenant faction - that the Forerunners are divine beings, that he is an "oracle" who provides divine revelation, and that the Halo installations are instruments of eternal salvation - with factual information."

On a separate note, I searched Halo and COVID when I made this post on Reddit, and got this post from the Coronavirus subreddit. Team Halo, helping end the pandemic. And also, there is haloverify.com, which offers the "world's most effective virus screening solution." "Get tested. Get verified. And get back to business."

"HALO™ is a British biotech that has developed a cheaper, more sensitive and faster saliva-based virus testing system designed to get business back to work as the world recovers from the COVID-19 crisis."

Any thoughts on the matter?